Immobilization stress effect on thyroid hormone secretion
https://doi.org/10.14341/probl11990
Abstract
Analysis of blood flowing from the rat thyroid has shown that an acute immobilization stress enhanced thyroid hormone secretion with an increase of the T3/T4-100 index. The most marked response to stress was observed after repeated 2 min immobilization with a 3 min interval: Such increase of secretion was arrested by injection of prasosin, an α-adrenoblocker. Propylthiouracil injected an hour before the experiment reduced T4 thyroid conversion index. These results permit a conclusion that short-term repeated immobilization enhanced thyroid hormone secretion via α-adrenergic system stimulation, this being paralleled by increased production of hormonally more active T3.
About the Authors
Ya. Kh. Turakulov
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
Uzbekistan
R. B. Burikhanov
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
Uzbekistan
P. P. Patkhitdinov
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
Uzbekistan
A. I. Myslitsksya
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
Uzbekistan
References
1. Васильев В. Н. Здоровье и стресс.- М., 1986.- С. 7-8.
2. Ведяев Ф. П., Воробьева Т. М. Модели и механизмы эмоциональных стрессов.- Киев, 1983.- С. 64.
3. Вигаш М. // Онтогенетические и генетико-эволюционные аспекты нейроэндокринной регуляции стресса.- Новосибирск, 1990.- С. 6-17.
4. Потемкин В. В. Эндокринология.- М., 1986.- С. 94-96.
5. Туракулов Я- X., Ташходжаева Т. П., Буриханов Р. Б. и др. // Пробл. эндокринол.- 1986.- Т. 32, № 5.- С. 72-76.
6. Фурдуй Ф. И. Физиологические механизмы стресса и адаптации при остром действии стресс-факторов.- Кишинев, 1986.- С. 16-24, 75-88.
7. Эверли Дж. С., Розенфельд Р. Стресс: Природа и лечение,- М., 1985.- С. 224.
8. Langer Р., VigaS М., Kvernansky R. // Acta endocr. (Kbh.).- 1983.- Vol. 10, N 4.- P. 443-449.
Review
For citations:
Turakulov Ya.Kh., Burikhanov R.B., Patkhitdinov P.P., Myslitsksya A.I. Immobilization stress effect on thyroid hormone secretion. Problems of Endocrinology. 1993;39(5):47-48. (In Russ.) https://doi.org/10.14341/probl11990
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