Effect of I-131 incorporation on male rat reproductive system and the dose-dependent effect
https://doi.org/10.14341/probl12016
Abstract
Radioactive 131I was injected in single doses 9.25, 37, and 92.5 kBq to prepubertal (30-day-old) male rats. Iodine incorporation in doses 37 and 92.5 kBq resulted in some functional changes in the reproductive system of mature rats: blood testosterone level increased, its hypothalamic aromatization intensified, and biologically active LH level in the blood dropped. Incorporation of 9.25 kBq of 131-I had no effect on male reproductive system. A possibility of direct injury to rat testicles by 131I incorporation is suggested.
About the Authors
L. V. Tarasenko
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
S. V. Varga
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
V. N. Demchenko
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
Ye. V. Bolshova
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
N. D. Nosenko
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
P. V. Sinitsyn
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
L. V. Chaikovskaya
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
A. G. Reznikov
Ukranian Scientific Institute for Endocrinology and Metabolism
Ukraine
Ukraine
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Review
For citations:
Tarasenko L.V., Varga S.V., Demchenko V.N., Bolshova Ye.V., Nosenko N.D., Sinitsyn P.V., Chaikovskaya L.V., Reznikov A.G. Effect of I-131 incorporation on male rat reproductive system and the dose-dependent effect. Problems of Endocrinology. 1994;40(3):45-47. (In Russ.) https://doi.org/10.14341/probl12016
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