Insulin content and arterial pressure in obese women
https://doi.org/10.14341/probl12067
Abstract
The pathogenesis of hypertension developing in obesity is still to be studied. Hyperinsulinism and insulin resistance are believed to contribute to it. A relationship between the levels of basal and glucose-stimulated immunoreactive insulin (IRI) and arterial pressure (AP) has been studied in 36 women aged 18 to 37 suffering from obesity of the first-fourth degrees. Basal IRI level was appreciably increased and directly correlating with systolic and diastolic AP, but not related to body weight excess. AP directly depended on the degree of obesity and disease standing, but not on patient's age. These data permit us to conclude that insulin contributes to the pathogenesis of hypertension in obese women, but further studies are needed to elucidate the type and mechanisms of this contribution.
About the Authors
M. M. Ginzburg
Samara State Medical University
Russian Federation
Russian Federation
G. S. Kozupitsa
Samara State Medical University
Russian Federation
Russian Federation
O. V. Sergeyev
Samara State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Ginzburg M.M., Kozupitsa G.S., Sergeyev O.V. Insulin content and arterial pressure in obese women. Problems of Endocrinology. 1996;42(4):17-19. (In Russ.) https://doi.org/10.14341/probl12067
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