Syndrome of hypocalсiuric hypercalcemia. Is it rare? Two clinical cases in an outpatient clinic
https://doi.org/10.14341/probl13125
Abstract
Hypocalciuric hypercalcemia syndrome (familial hypocalciuric hypercalcemia, FHH) is an inherited condition based on dysfunction of the calcium receptor or its associated partner proteins. Recent evidence suggests that the prevalence of this condition may be comparable to that of primary hyperparathyroidism. Clinical manifestations of FHH are usually absent; however the classic symptoms of hypercalcemia may be present in some cases. Timely differential diagnosis of FHH avoids unnecessary and expensive instrumental examination, as well as ineffective treatment. The clinical cases presented in this publication demonstrate the unjustified difficulties in this issue and the necessity to raise the awareness of physicians about the familial hypocalciuric hypercalcemia.
About the Author
M. A. Sviridonova
LLC “Ogni Olimpa”
Russian Federation
Competing Interests:
Russian Federation
Marina A. Sviridonova - MD, PhDю
125124, 15/4 1th street Yamskogo Polya, Moscow.
SPIN-код: 3717-2510
Competing Interests:
None
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1. Figure 1. Calcium homeostasis in the body. | |
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2. Figure 2. Functioning of the calcium-sensing receptor. | |
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For citations:
Sviridonova M.A. Syndrome of hypocalсiuric hypercalcemia. Is it rare? Two clinical cases in an outpatient clinic. Problems of Endocrinology. 2022;68(5):24-31. (In Russ.) https://doi.org/10.14341/probl13125
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