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Features of water-electrolyte balance in persons of the older age group

https://doi.org/10.14341/probl13214

Abstract

Age-related changes have a great influence on the regulation of water and electrolyte homeostasis in the body, which is regulated by a complex interaction of environmental factors, drinking behavior, the secretion of a number of hormones and hormone-like substances, as well as the innervation and functional state of the kidneys. It is well known that the changes that are part of physiological aging underlie fluid and electrolyte imbalances, exacerbated by the presence of age-related diseases, medications, or a number of external factors such as malnutrition, fluid intake, and the presence of dementia. This review considers literature data on the effect of normal aging on the development of pathology of the water-sodium balance, including dehydration of senile patients, hyponatremia, hypernatremia, changes in the secretion of antidiuretic hormone and the activity of elements of the renin-angiotensin-aldosterone system.

About the Authors

N. N. Katamadze
Endocrinology Research Centre
Russian Federation

Nino N. Katamadze]

Dmitry Ulyanova street 11, bld. 2, 117036 Moscow


Competing Interests:

none



E. A. Pigarova
Endocrinology Research Centre
Russian Federation

Ekaterina A. Pigarova - MD, PhD.

Moscow


Competing Interests:

none



L. K. Dzeranova
Endocrinology Research Centre
Russian Federation

Larisa K. Dzeranova - MD, PhD.

Moscow


Competing Interests:

none



N. G. Mokrysheva
Endocrinology Research Centre
Russian Federation

Natalia G. Mokrysheva - MD, PhD, Professor.

Moscow


Competing Interests:

none



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For citations:


Katamadze N.N., Pigarova E.A., Dzeranova L.K., Mokrysheva N.G. Features of water-electrolyte balance in persons of the older age group. Problems of Endocrinology. 2023;69(6):28-36. (In Russ.) https://doi.org/10.14341/probl13214

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