Association between treatment outcome and age in tuberculosis and diabetes patients: a population analysis
https://doi.org/10.14341/probl13252
Abstract
Background. The undoubted importance of this work lies in the fact that for the first time in the Republic of Kazakhstan, an analysis is being made of the relationship between age and treatment outcome in patients with a comorbid diagnosis of tuberculosis and diabetes mellitus.
Purpose of the study. Identification of the correlation between the age of patients with tuberculosis with diabetes mellitus and the outcome of treatment.
Materials and methods. Cross-sectional retrospective study of 2,125 patients with TB and diabetes mellitus out of a total of 43,807 of all patients diagnosed with TB (2017-2019). The study analyzed the data of patients with comorbidity from all regions of Kazakhstan (data from 14 regions and 3 cities of republican significance) (2017-2019).
Results. A high prevalence of tuberculosis morbidity with a concomitant diagnosis of diabetes mellitus in the age group from 45 to 64 years was revealed. This group consisted of 1193 patients out of 2115 (56.4% of the total number of patients with tuberculosis and diabetes mellitus). The average age of all studied patients with DM was 54.7±13.4 years. There is a positive correlation between age and treatment outcome in TB patients. Mortality was higher in the age group over 45 years old – OR95%CI = 0.213 [0.019–2.362], p – 0.0000015 (p < 0.05).
About the Authors
L. T. Yeraliyeva
Kazakh National Medical University» named after S.D. Asfendiyarov; National Scientific Center for Phthisiopulmonology of the Republic of Kazakhstan
Kazakhstan
Competing Interests:
Kazakhstan
Lyazzat T. Yeraliyeva, DMedSc, professor
Scopus Author ID: 57809431200
SPIN-код: 1166-3710
Almaty city, Bekkhozhin street, 5, 050010
Competing Interests:
None
A. M. Issayeva
Kazakh National Medical University» named after S.D. Asfendiyarov
Kazakhstan
Competing Interests:
Kazakhstan
Assiya M. Issayeva, MD
SPIN-код: 7085-4977
Almaty
Competing Interests:
None
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Supplementary files
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1. Figure 1. Step-by-step method for compiling a database of patients with comorbid diagnoses for further use in statistical software | |
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2. Figure 2. Distribution of patients with tuberculosis and diabetes mellitus by age structure, categorized by years of treatment (absolute numbers) | |
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3. Figure 3. Treatment outcomes of patients with diabetes and TB for all age groups studied (percentages) | |
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| Type | Исследовательские инструменты | |
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Review
For citations:
Yeraliyeva L.T., Issayeva A.M. Association between treatment outcome and age in tuberculosis and diabetes patients: a population analysis. Problems of Endocrinology. 2023;69(5):93-98. (In Russ.) https://doi.org/10.14341/probl13252
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