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A personalized, evidence-based approach to obesity therapy using clinical algorithms: semaglutide or tirzepatide

https://doi.org/10.14341/probl13677

Abstract

On June 26, 2025, a meeting of the expert working group was held in Moscow. The discussion focused on the personalized approach of tirzepatide («Tirzetta®») and semaglutide («Velgia Eco®») in patients with excess body weight, obesity, and type 2 diabetes. Following the meeting, the objective was set to develop a consensus-based algorithm for prescribing these drugs to ensure their effective use in Russian clinical practice.

About the Authors

E. A. Troshina
Endocrinology Research Centre
Russian Federation

Ekaterina A. Troshina, MD, PhD, Professor

Moscow, st. Dmitry Ulyanov 11, 117292



M. B. Antsiferov
Endocrinological Dispensary
Russian Federation

Mikhail B. Antsiferov, MD, PhD

Moscow



A. S. Ametov
Russian Medical Academy of Continuing Professional Education
Russian Federation

Alexander S. Ametov, MD, PhD, Professor

Moscow



G. R. Galstyan
Endocrinology Research Centre
Russian Federation

Gagik R. Galstyan, MD, PhD, Professor

Moscow



T. N. Markova
Russian University of Medicine
Russian Federation

Tatiana N. Markova

Moscow



T. I. Romantsova
Russian Medical Academy of Continuing Professional Education
Russian Federation

Tatiana I. Romantsova, MD, PhD, Professor

Moscow



N. V. Mazurina
Endocrinology Research Centre
Russian Federation

Natalya V. Mazurina, MD. PhD

Moscow



O. M. Koteshkova
Endocrinological Dispensary
Russian Federation

Olga M. Koteshkova, MD, PhD

Moscow



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Review

For citations:


Troshina E.A., Antsiferov M.B., Ametov A.S., Galstyan G.R., Markova T.N., Romantsova T.I., Mazurina N.V., Koteshkova O.M. A personalized, evidence-based approach to obesity therapy using clinical algorithms: semaglutide or tirzepatide. Problems of Endocrinology. 2025;71(5):19-30. (In Russ.) https://doi.org/10.14341/probl13677

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