Взаимосвязь соматотропной функции гипофиза и иммунной системы и их роль в развитии неоплазий


Представлены данные о связи гормона роста (ГР) с иммунной системой. Обсуждается влияние ростовых факторов на популяционный и субпопуляционный состав CD-экспрессирующих лимфоцитов, функциональную активность клеток иммунной системы, модуляцию апоптоза. Подробно описана роль нарушений соматотропной функции гипофиза и иммунной системы в генезе развития неопластических процессов. Изменения в иммунной системе при хронической гиперсекреции ростовых факторов, а также тесные иммуноэндокринные взаимодействия представляются важными факторами патогенеза нео­плазий, непосредственно влияющими на выживаемость больных при акромегалии.

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Для цитирования:

., ., . Взаимосвязь соматотропной функции гипофиза и иммунной системы и их роль в развитии неоплазий. Проблемы Эндокринологии. 2013;59(1):30-34.

For citation:

Dogadin S.A., Dudina M.A., Savchenko A.A. The relationship between the pituitary somatotrophic function and the immune system, its role in the development of neoplasia. Problems of Endocrinology. 2013;59(1):30-34. (In Russ.)

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