The role of YY3-36 peptide in the regulation of body weight in patients presenting with the exogenous constitutional form of obesity
https://doi.org/10.14341/probl201157413-16
Abstract
References
1. Schwartz M.W., Woods S.C., Porte D. Jr. et al. Central nervous system control of food intake. Nature 2000; 404: 6778: 661-671.
2. Konturek P.C., Konturek J.W., Cześnikiewicz-Guzik M. et al. Neuro-hormonal control of food intake: basic mechanisms and clinical implications. J Physiol Pharmacol 2005; 56: Suppl 6: 5-25.
3. Sahu A. Minireview: A hypothalamic role in energy balance with special emphasis on leptin. Endocrinology 2004; 145: 6: 2613-2620.
4. Batterham R.L., Cowley M.A., Small C.J. et al. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 2002; 418: 6898: 650-654.
5. Tatemoto K., Mutt V. Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature 1980; 285: 5764: 417-418.
6. Batterham R.L., Cohen M.A., Ellis S.M. et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003; 349: 10: 941-948.
7. Grandt D., Schimiczek M., Beglinger C. et al. Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36. Regul Pept 1994; 51: 2: 151-159.
8. Frayn K.N. Metabolic regulation. A human perspective. Blackwel Publisching Company. Oxford United Kingdom 2003; 441-446.
9. Helou N., Obeid O., Azar S.T. et al. Variation of postprandial PYY 3-36 response following ingestion of differing macronutrient meals in obese females. Ann Nutr Metab 2008; 52: 3: 188-195.
10. Беляков Н.А., Мазурова В.И. Ожирение. Руководство для врачей. Ст-Петербург 2003; 8-9.
11. Viardot A., Heilbronn L.K., Herzog H. et al. Abnormal postprandial PYY response in insulin sensitive nondiabetic subjects with a strong family history of type 2 diabetes. Int J Оbes 2008; 32: 6: 943-948.
12. Xu J., McNearney T.A., Chen J. Impaired postprandial releases/syntheses of ghrelin and PYY(3-36) and blunted responses to exogenous ghrelin and PYY(3-36) in a rodent model of diet-induced obesity. J Gastroenterol Hepatol 2011; 26: 4: 700-705.
13. Dalia El Khoury D., Rola El-Rassi R., Azar S., Hwalla N. Postprandial grelin and PYY responses of male subjects on low carbohydrate meals to varied balancing proportions of proteins and fats. Eur J Nutr 2010; 49: 8: 493-500.
14. Everitt B.J., Hokfelt T., Terenius L. et al. Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat. Neuroscience 1984; 11: 2: 443-462.
15. Harfstrand A., Eneroth P., Agnati L., Fuxe K. Further studies on the effects of central administration of neuropeptide Y on neuroendocrine function in the male rat: relationship to hypothalamic catecholamines. Regul Pept 1987; 17: 3: 167-179.
16. Kubota Y., Inagaki S., Kito S. et al. Neuropeptide Y-immunoreactive neurons receive synaptic inputs from dopaminergic axon terminals in the rat neostriatum. Brain Res 1988; 458: 2: 389-393.
17. Sahu A., Kalra S.P., Crowley W.R., Kalra P.S. Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain Res 1988; 457: 2: 376-378.
18. Boey D., Lin S., Karl T. et al. Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity. Diabetologia 2006; 49: 6: 1360-1370.
Review
For citations:
Vlasova I.I., Ametov A.S. The role of YY3-36 peptide in the regulation of body weight in patients presenting with the exogenous constitutional form of obesity. Problems of Endocrinology. 2011;57(4):13-16. https://doi.org/10.14341/probl201157413-16
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).
Email this article 
.jpg){kind=logo}
