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Диагностика и лечение эутиреоидного зоба: место комбинированной терапии препаратами йода и левотироксина

https://doi.org/10.14341/probl201258242-51

Об авторе

V Fadeev



Список литературы

1. Дедов И.И., Мельниченко Г.А., Трошина Е.А. и др. Дефицит йода - угроза развитию и здоровью детей России (Национальный доклад). ЮНИСЕФ, 2006.

2. Фадеев В.В. Заболевания щитовидной железы в регионе легкого йодного дефицита: эпидемиология, диагностика, лечение. М: Видар-М 2005.

3. Фадеев В.В. Эутиреоидный зоб. Патогенез, диагностика, лечение. Клин тиреоидол 2003; 1: 3-13.

4. Marine D., Kimball O.P. Prevention of simple goiter in man. Arch Int Med 1920; 25: 661-672.

5. Marine D. The pathogenesis and prevention of simple or endemic goiter. JAMA 1935; 104: 2334.

6. Bray G.A. Increased sensitivity of the thyroid in iodine-depleted rats to the goitrogenic effects of thyrotropin. J Clin Inv 1968; 47: 1640-1647.

7. Gutekunst R., Smolarek H., Hasenpusch U. et al. Goitre epidemiology: thyroid volume, iodine excretion, thyroglobulin and thyrotropin in Germany and Sweden. Acta Endocrinol 1986; 112: 494-501.

8. Hintze G., Emrich D., Köbberling J. Treatment of endemic goitre due to iodine deficiency with iodine, levothyroxine or both: results of a multicentre trial. Eur J Clin Inv 1989; 19: 527-534.

9. Hofbauer L.C., Rafferzeder M., Janssen O.E., Gärtner R. Insulin-like growth factor I messenger ribonucleic acid expression in porcine thyroid follicles is regulated by thyrotropin and iodine. Eur J Endocrinol 1995; 132: 605-610.

10. Gärtner R., Greil W., Demharter R., Horn K. Involvement of cyclic AMP, iodide and metabolites of arachidonic acid in the regulation of cell proliferation of isolated porcine thyroid follicles. Mol Cell Endocrinol 1985; 42: 145-155.

11. Maciel R.M., Moses A.C., Villone G. et al. Demonstration of the production and physiological role of insulin-like growth factor II in rat thyroid follicular cells in culture. J Clin Inv 1988; 82: 1546-1553.

12. Laurberg P., Nyhr S.B., Pedersen K.M. et al. Thyroid disorders in mild iodine deficiency. Thyroid 2000; 10: 951-963.

13. Einenkel D., Bauch K.H., Benker G. Treatment of juvenile goitre with levothyroxine, iodide or a combination of both: the value of ultrasound grey-scale analysis. Acta Endocrinol (Copenh) 1992; 127: 301-306.

14. Hintze G., Koebberling J. Treatment of iodine deficiency goiter with iodine, levothyroxine or a combination of both. Thyroidology 1992; 4: 37-40.

15. Foerster G., Krummenauer F., Hansen C. et al. Individually dosed levothyroxine with 150 micrograms iodide versus 100 micrograms levothyroxine combined with 100 micrograms iodide. A randomized double-blind trial. Dtsch Med Wochenschr 1998; 29: 685-689.

16. Räher H.D., Horster F.A. Therapie einer Funktionsstärung nach Schilddrüsenoperation. Dtsch Med Wochenschr 1986; 111: 674-676.

17. Saller B., Hoermann R., Ritter M.M. et al. Course of thyroid iodine concentration during treatment of endemic goitre with iodine and a combination of iodine and levothyroxine. Acta Endocrinol (Copenh) 1991; 125: 662-667.

18. Grussendorf M. Therapy of euthyroid iron deficiency goiter. Effectiveness of a combination of L-thyroxine and 150 micrograms iodine in comparison with mono-L-thyroxine. Med Klin 1996; 15: 814.

19. Pfannenstiel P. Therapie der endemischen Struma mit Levothyroxin und Jodid. Ergebnisse einer multizentrischen Studie. Dtsch Med Wochenschr 1988; 113: 326-331.

20. Kreissl M., Tiemann M., Haenscheid H. et al. Comparison of the effectiveness of two different dosages of levothyroxine-iodide combinations for the therapy of euthyroid diffuse goiter. Dtsch Med Wochenschr 2001; 126: 227-231.

21. Hotze L.A., Wegscheider K. Comparative study with 2 L-thyroxine-iodide combinations. Iodine deficient goiter can be decreased also with less thyroxine. MMW Fortschr Med 2002; 144: 53.

22. Klemenz B., Foerster G., Wieler H. et al. Combination therapy of endemic goiter with two different thyroxine/iodine combinations. Nuklearmedizin 1998; 37: 101-106.

23. Foerster G., Hansen C., Mairsch F. et al. Bioequivalence of a combination of levothyroxine and iodine in comparison with levothyroxine only. A controlled double-blind study of bioavailability. Med Klin (Munich) 1998; 15: 401-406.

24. Schumm-Draeger P.M. Drug therapy of goiter. Iodine, thyroid hormones or combined therapy. Inn Med 1993; 48: 592-598.

25. Fritsche H. Die resezierte Struma: Diagnose, Rezidivprophylaxe, Therapie. Acta Med Austr 1986; 13: Suppl 34: 2-38.

26. Kologlu S., Baskal N., Kologlu L.B. The value of thyroxine in the suppressive therapy of euthyroid nodules and in the prevention of post-thyroidectomy recurrences. Rom J Med 1988; 26: 89-98.

27. Carella C., Mazziotti G., Rotondi M. et al. Iodized salt improves the effectiveness of L-thyroxine therapy after surgery for nontoxic goitre: a prospective and randomized study. Clin Endocrinol (Oxf) 2002; 57: 507-513.

28. Feldkamp J., Seppel T., Becker A. et al. Iodide or L-thyroxine to prevent recurrent goiter in an iodine-deficient area: prospective sonographic study. World J Surg 1997; 21: 10-14.

29. Rotondi M., Amato G., Del Buono A. et al. Postintervention serum TSH levels may be useful to differentiate patients who should undergo levothyroxine suppressive therapy after thyroid surgery for multinodular goiter in a region with moderate iodine deficiency. Thyroid 2000; 10: 1081-1085.

30. Schumm-Draeger P.M., Encke A., Usadel K.H. Optimal recurrence prevention of iodine deficiency related goiter after thyroid gland operation. A prospective clinical study. Internist (Berl) 2003; 44: 420-426, 429-432.

31. Feldkamp J., Röher H.D., Scherbaum W.A. Rezidivprophylaxe und medikamentöse Therapiestrategien nach Operationen an der Schilddrüse. Deutsches Ärzteblatt 1998; 95: Heft 38: A2324-A2328.


Для цитирования:


. Диагностика и лечение эутиреоидного зоба: место комбинированной терапии препаратами йода и левотироксина. Проблемы Эндокринологии. 2012;58(2):42-51. https://doi.org/10.14341/probl201258242-51

For citation:


Fadeev V.V. Diagnostics and treatment of non-toxic goiter: the place of combined therapy with iodine and levothyroxine. Problems of Endocrinology. 2012;58(2):42-51. (In Russ.) https://doi.org/10.14341/probl201258242-51

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