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Окислительный стресс при сахарном диабете 2-го типа и пути его коррекции

https://doi.org/10.14341/probl201157652-56

Аннотация

В последние годы среди механизмов развития поздних сосудистых осложнений сахарного диабета 2-го типа особое значение придается окислительному стрессу. Более того, окислительный стресс, индуцированный гипергликемией, рассматривается в качестве главного механизма повреждения β-клеток, ускоряющего прогрессирование сахарного диабета. Современные гипогликемические препараты должны обладать дополнительными свойствами, препятствующими развитию сосудистых осложнений. Одним из препаратов, обладающим антиатерогенными и антиоксидантными свойствами, увеличивающим выживаемость β-клеток в условиях окислительного стресса и резистентность ЛПНП к окислению, является гликлазид МВ.

Об авторах

A Ametov



O Solov'eva



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Для цитирования:


., . Окислительный стресс при сахарном диабете 2-го типа и пути его коррекции. Проблемы Эндокринологии. 2011;57(6):52-56. https://doi.org/10.14341/probl201157652-56

For citation:


Ametov A.S., Solov'eva O.L. Oxidative stress in type 2 diabetes mellitus and methods for its correction. Problems of Endocrinology. 2011;57(6):52-56. (In Russ.) https://doi.org/10.14341/probl201157652-56

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