Тиазолидиндионы: долгая дорога в клинику

Клиническое использование тиазолидиндионов насчитывает около 12 лет. Коррекция углеводного обмена при их применении сопровождается улучшением многих факторов риска ИБС и прогноза больных сахарным диабетом 2-го типа. Обсуждаются возможные механизмы осложнений, выявленных в клинике при применении ряда тиазолидиндионов.

сахарный диабет 2-го типа, тиазолидиндионы, пероксисомы, свободнорадикальное окисление, инсулинорезистентность, сердечно-сосудистые осложнения, гепатит, инфаркт миокарда

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