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The treatment of acromegaly with long-acting octreotide: the effective control of disease activity and decrease of the tumour volume

https://doi.org/10.14341/probl20125843-7

Abstract

The objective of the present retrospective study was to evaluate the results of the long-term treatment of the patients suffering from active acromegaly with octreotide. It included a total of 48 patients at the age from 30 to 77 years (15 men and 33 women) of whom 18.7% and 81.2% presented with pituitary microadenoma and macroadenoma respectively. All the patients were given long-acting octreotide either as primary or as adjuvant therapy at a dose of 20-40 mg once every 28 days for 3 years. The treatment resulted in the remission in 9 (100%) patients having pituitary microadenoma and 9 (23%) ones with macroadenoma. By the end of the 3-year treatment period the clinically significant decease of the tumour volume was documented in 9 (100%) and 32 (82%) patients presenting with microadenoma and macroadenoma, respectively.

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Review

For citations:


Dogadin S.A., Dudina M.A., Lobyntseva L.A. The treatment of acromegaly with long-acting octreotide: the effective control of disease activity and decrease of the tumour volume. Problems of Endocrinology. 2012;58(4):3-7. https://doi.org/10.14341/probl20125843-7

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)