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The efficacy of application of vildagliptin in the patints presenting with co-morbid pathology

https://doi.org/10.14341/probl201258341-45

Abstract

The patients presenting with type 2 diabetes mellitus (DM2) not infrequently have concomitant diseases of the cardiovascular, respiratory, digestive, and urogenital systems which hampers the choice of optimal hypoglycemic therapy. The prescription of insulin injections appears to be the most natural and efficacious modality of such therapy. However, excessive doses of insulin are known to cause hypoglycemia and body weight increment. Hypoglycemia interferes with the optimal control of the diabetic patients' conditions especially in those of advanced age who may poorly respond to the treatment. In the present study, the intake of vildagliptin in combination with insulin administration resulted in the significant improvement of the characteristics of carbohydrate and lipid metabolism in the absence of overweight, with the minimal risk of hypoglycemia and cardiovascular diseases (complications).

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Review

For citations:


Vertkin A.L., Magomedova A.I., Mychka V.B., Prokhorova I.V., Nosova A.V. The efficacy of application of vildagliptin in the patints presenting with co-morbid pathology. Problems of Endocrinology. 2012;58(3):41-45. https://doi.org/10.14341/probl201258341-45

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)