Антимюллеров гормон (АМГ) у девочек-подростков с гипер­андрогенией


Антимюллеров гормон (АМГ) является надежным маркером нарушений фолликулогенеза. В статье освещены результаты определения АМГ у 57 девочек-подростков с различными вариантами течения гиперандрогении, его взаимосвязь с выраженностью клинических симптомов и уровнем андрогенов в периферической крови.

Список литературы

1. Azziz R., Carmina E., Dewailly D. The androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete taskforse report. Fertil Steril 2009; 91: 456-488.

2. The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Hum Reprod 2007; 19: 41-47.

3. Kumar A., Woods K., Bartolucci A., Azziz R. Prevalence of Adrenal Androgen Excess in Patients with PCOS: Discussion. Clin Endocrinol 2005; 62: 6: 644-649.

4. Ibanez L., DiMartino-Nardi J., Potau N. Premature adrenarche - normal variant or forerunner of adult disease? Endocrine Reviews 2000; 21: 671-696.

5. Bern V., Picard J.Y., Dien T., Laur L., Nath J. Production of Anti-Mullerian Hormone: Another Homology between Sertoli and Granulosa Cells. Endocrinology 1984; 114: 1315-1320.

6. La Marca A., Broekmans F.J., Volpe A., Fauser B.C., Macklon N.S. Anti-Mullerian hormone (AMH): what do we still need to know? Human Reproduction 2009; 24: 2264-2275.

7. Piltonen T., Morin-Papunen L., Koivunen R., Perheentupa A., Ruokonen A., Tapanainen J.S. Serum anti-Mullerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome. Human Reprod 2005; 20: 1820-1826.

8. Catteau-Jonard S., Jamin S.P., Leclerc A., Gonzales J., Dewailly D., di Clemente N. Anti-Mullerian Hormone, Its Receptor, FSH Receptor, and Androgen Receptor Genes Are Overexpressed by Granulosa Cells from Stimulated Follicles in Women with Polycystic Ovary Syndrome. J Clin Endocrinol Metab 2008; 93: 4456-4461.

9. Pellatt L., Rise S., Mason H. Anti-Mullerian hormone and polycystic ovary syndrome: a mountain too high? Reproduction 2010; 39: 5: 825-833.

10. Nardo L.G., Yates A.P., Roberts S.A., Pemberton P., Laing I. The relationships between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without polycystic ovary syndrome. Human Reprod 2009; 24: 2917-2923.

11. Piouka A., Farmakiotis D., Katsikis I., Macut D., Gerou S., Panidis D. Anti-Mullerian hormone levels reflect severity of PCOS but are negatively influenced by obesity: relationship with increased luteinizing hormone levels. Am J Phys Endocrinol Metabol 2009; 296: E238-E243.

12. Carlsen S.M., Vanky E., Fleming R. Anti-Mullerian hormone concentrations in androgen-suppressed women with polycystic ovary syndrome. Human Reprod 2009; 24: 1732-1738.

13. Jayaprakasan K., Campbell B., Hopkisson J., Johnson I., Raine-Fenning N. A prospective, comparative analysis of anti-Mullerian hormone, inhibin-B, and three-dimensional ultrasound determinants of ovarian reserve in the prediction of poor response to controlled ovarian stimulation. Fertil Steril 2010; 93: 3: 855-864.

14. Laven J., Mulders A., Visser J., Themmen A., de Jong F., Fauser B. Anti-Mullerian Hormone Serum Concentrations in Normoovulatory and Anovulatory Women of Reproductive Age. J Clin Endocrinol Metab 2004; 89: 318-323.

15. Siow Y., Kives S., Hertweck P., Perlman S., Fallat M.E. Serum mullerian-inhibiting substance levels in adolescent girls with normal menstrual cycles or with polycystic ovary syndrome. Fertil Steril 2005; 84: 4: 938-944.

16. Balen A., Laven J., Tan S. Ultrasound assessment of polycystic ovary: international consensus definitions. Human Reprod Update 2003; 9: 6: 505-514.

17. Deplewski D., Rosenfeld R. Role of Hormones in Pilosebaceous Unit Development. Endocrine Reviews 2000; 21: 4: 363-392.

18. Stener-Victorin E., Holm G., Labrie F. Are There Any Sensitive and Specific Sex Steroid Markers for Polycystic Ovary Syndrome? J Clin Endocrinol Metab 2010; 95: 2: 810-819.

19. Legro R.S., Schlaff W.D., Diamond M.P., Coutifaris C., Casson P.R., Brzyski R.G., Christman G.M., Trussell J.C., Krawetz S.A., Snyder P.J., Ohl D., Carson S.A., Steinkampf M.P., Carr B.R., McGovern P.G., Cataldo N.A., Gosman G.G., Nestler J.E., Myers E.R., Santoro N., Eisenberg E., Zhang M., Zhang H. for the Reproductive Medicine Network. Total Testosterone Assays in Women with Polycystic Ovary Syndrome: Precision and Correlation with Hirsutism. J Clin Endocrinol Metab 2010; 95: 5305-5313.

20. Гончаров Н.П., Кация Г.В. Современные методы определения тестостерона. Вестн репрод здоровья 2008; 1: 31-37.

21. Rosner W., Vesper H. On behalf of The Endocrine Society the endorsing organizations. Toward Excellence in Testosterone Testing: A Consensus Statement. J Clin Endocrinol Metab 2010; 95: 4542-4548.

22. Dewailly D., Pigny P., Soudan B., Catteau-Jonard S., Decanter C., Poncelet E., Duhamel A. Reconciling the Definitions of Polycystic Ovary Syndrome: The Ovarian Follicle Number and Serum Anti-M+-llerian Hormone Concentrations Aggregate with the Markers of Hyperandrogenism. J Clin Endocrinol Metab 2010; 95: 4399-4405.

Для цитирования:

., ., ., ., ., . Антимюллеров гормон (АМГ) у девочек-подростков с гипер­андрогенией. Проблемы Эндокринологии. 2012;58(1):9-16.

For citation:

Bogdanova P.S., Kareva M.A., Iarovaia I.S., Zlotnikova O.A., Il'in A.V., Dedov I.I. Anti-Mullerian hormone (AMH) in the adolescent girls presenting with hyperandrogenism. Problems of Endocrinology. 2012;58(1):9-16. (In Russ.)

Просмотров: 21

Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.

ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)