Проблемы Эндокринологии

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"Внутриутробное программирование" гормонально-метабо­лических процессов и синдром задержки внутриутробного развития


Гипотеза о "фетальном программировании" предполагает, что адаптация плода в ответ на недостаток питания приводит к стойким изменениям метаболизма, которые превращаются в предрасположенность к сердечно-сосудистым, метаболическим и эндокринным заболеваниям. К настоящему времени накоплено достаточно много катамнестических данных о том, что у людей с пренатальной задержкой роста в анамнезе в зрелом возрасте возможно развитие различных гормонально-метаболических нарушений: выявлена тесная связь между синдромом задержки внутриутробного развития и повышенным артериальным давлением, нарушенной толерантностью к глюкозе, метаболическим синдромом. В обзоре обобщены данные эпидемиологических и экспериментальных исследований, подтверждающие данную гипотезу.

Об авторах

E Nagaeva

T Shiriaeva

Список литературы

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Для цитирования:

., . "Внутриутробное программирование" гормонально-метабо­лических процессов и синдром задержки внутриутробного развития. Проблемы Эндокринологии. 2010;56(6):32-40.

For citation:

Nagaeva E.V., Shiriaeva T.I. "Intrauterine programming" of hormonal and metabolic processes and intrauterine growth retardation syndrome. Problems of Endocrinology. 2010;56(6):32-40. (In Russ.)

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