"Внутриутробное программирование" гормонально-метабо­лических процессов и синдром задержки внутриутробного развития

Гипотеза о "фетальном программировании" предполагает, что адаптация плода в ответ на недостаток питания приводит к стойким изменениям метаболизма, которые превращаются в предрасположенность к сердечно-сосудистым, метаболическим и эндокринным заболеваниям. К настоящему времени накоплено достаточно много катамнестических данных о том, что у людей с пренатальной задержкой роста в анамнезе в зрелом возрасте возможно развитие различных гормонально-метаболических нарушений: выявлена тесная связь между синдромом задержки внутриутробного развития и повышенным артериальным давлением, нарушенной толерантностью к глюкозе, метаболическим синдромом. В обзоре обобщены данные эпидемиологических и экспериментальных исследований, подтверждающие данную гипотезу.

фетальное программирование, задержка внутриутробного развития, рост плода, нутритивный статус, метаболический синдром

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