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Врожденный гиперинсулинизм

https://doi.org/10.14341/probl201056641-47

Аннотация

Врожденный гиперинсулинизм (ВГИ) - одна из основных причин развития персистирующих гипогликемических состояний в детском возрасте. Биохимически ВГИ характеризуется неадекватной гиперсекрецией инсулина β-клетками поджелудочной железы. ВГИ является гетерогенным заболеванием в отношении как клинических проявлений и морфологических форм, так и молекулярно-генетических дефектов, лежащих в его основе. В настоящей статье изложены современные взгляды на основные механизмы развития ВГИ, представлена клиническая характеристика заболевания, предложены международные протоколы обследования и лечения детей, страдающих данной патологией.

Об авторе

M Melikian



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Для цитирования:


. Врожденный гиперинсулинизм. Проблемы Эндокринологии. 2010;56(6):41-47. https://doi.org/10.14341/probl201056641-47

For citation:


Melikian M.A. Congenital hyperinsulinism. Problems of Endocrinology. 2010;56(6):41-47. (In Russ.) https://doi.org/10.14341/probl201056641-47

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