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Эндокринная офтальмопатия: современный взгляд

https://doi.org/10.14341/probl201258624-32

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Аннотация

Обсуждаются вопросы этиологии, патогенеза, клинических проявлений и лечения эндокринной офтальмопатии (ЭОП). ЭОП — гетерогенное аутоиммунное заболевание глаз, которое чаще всего ассоциировано с болезнью Грейвса, но также встречается при хроническом аутоиммунном тиреоидите и в отсутствие дисфункции щитовидной железы. Хотя патогенез ЭОП остается не до конца ясным, несомненной является ее аутоиммунная природа с участием сенсибилизированных Т-лимфоцитов и аутоантител к тканям орбиты. Понимание механизмов развития ЭОП привело к появлению новых групп препаратов, действующих селективно на различные звенья патогенеза. Управление ЭОП остается сложной задачей, требующей мультидисциплинарного подхода.

Об авторах

N. Petunina
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ, Москва
Россия


L. Trukhina
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ, Москва
Россия


N. Martirosyan
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ, Москва
Россия


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Для цитирования:


., ., . Эндокринная офтальмопатия: современный взгляд. Проблемы Эндокринологии. 2012;58(6):24-32. https://doi.org/10.14341/probl201258624-32

For citation:


Petunina N.A., Trukhina L.V., Martirosyan N.S. Endocrine ophthalmopathy: state-of-the-art approaches. Problems of Endocrinology. 2012;58(6):24-32. (In Russ.) https://doi.org/10.14341/probl201258624-32

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