The new paradigm of obesity
https://doi.org/10.14341/probl201460543-48
Abstract
Despite the well-proved relationship between obesity and a number of chronic diseases, the information about the influence of the body weight on the life expectancy is contradictory. A wealth of literature publications deal with the paradoxical relation of the survival rate to obesity that manifests itself among the patients with the elevated body mass index (BMI) and moderate obesity as opposed to the patients having the normal or lowered BMI. The American Association of Endocrinologists proposed the new paradigm of the evaluation of BMI and obesity. The consensus of the Russian specialists as regards this paradigm needs to be reached in conjunction with the development of the relevant guidelines for practicing healthcare providers.
About the Author
I V Samorodskaya
State Research Centre of Prophylactic Medicine, Moscow
Russian Federation
Russian Federation
References
1. World Health Organization: Fact Sheet No. 311 (May 2012). www.who.int/mediacentre/factsheets/fs311/en/
2. Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, et al. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9•1 million participants. The Lancet. 2011;377(9765):557-567. doi: 10.1016/s0140-6736(10)62037-5
3. Дедов И.И., Мельниченко Г.А. Ожирение. Руководство для врачей. – М.: МИА; 2004. – 456 с. [Dedov II, Mel’nichenko GA. Obesity. Guidelines for physicians. Moscow: MIA; 2004. 456p. ]
4. Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1•8 million participants. The Lancet. 2014;383(9921):970-983. doi: 10.1016/s0140-6736(13)61836-x
5. Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW. Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults. New England Journal of Medicine. 1999;341(15):1097-1105. doi: 10.1056/nejm199910073411501
6. Durazo-Arvizu R, Cooper RS, Luke A, Prewitt TE, Liao Y, McGee DL. Relative weight and mortality in U.S. blacks and whites: Findings from representative national population samples. Annals of Epidemiology. 1997;7(6):383-395. doi: 10.1016/s1047-2797(97)00044-6
7. Zheng W, McLerran DF, Rolland B, Zhang X, Inoue M, Matsuo K, et al. Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians. New England Journal of Medicine. 2011;364(8):719-729. doi: 10.1056/NEJMoa1010679
8. Badheka AO, Rathod A, Kizilbash MA, Garg N, Mohamad T, Afonso L, et al. Influence of Obesity on Outcomes in Atrial Fibrillation: Yet Another Obesity Paradox. The American Journal of Medicine. 2010;123(7):646-651. doi: 10.1016/j.amjmed.2009.11.026
9. Carnethon MR, De Chavez PJD, Biggs ML, Lewis CE, Pankow JS, Bertoni AG, et al. Association of Weight Status With Mortality in Adults With Incident Diabetes. JAMA. 2012;308(6). doi: 10.1001/jama.2012.9282
10. Ma SH, Park B-Y, Yang JJ, Jung E-J, Yeo Y, Whang Y, et al. Interaction of Body Mass Index and Diabetes as Modifiers of Cardiovascular Mortality in a Cohort Study. Journal of Preventive Medicine & Public Health. 2012;45(6):394-401. doi: 10.3961/jpmph.2012.45.6.394
11. Tseng C-H. Obesity paradox: Differential effects on cancer and noncancer mortality in patients with type 2 diabetes mellitus. Atherosclerosis. 2013;226(1):186-192. doi: 10.1016/j.atherosclerosis.2012.09.004
12. Logue J, Walker JJ, Leese G, Lindsay R, McKnight J, Morris A, et al. Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality. Diabetes Care. 2012;36(4):887-893. doi: 10.2337/dc12-0944
13. Lakka HM, Lakka TA, Tuomilehto J, Salonen JT. Abdominal obesity is associated with increased risk of acute coronary events in men. European Heart Journal. 2002;23(9):706-713. doi: 10.1053/euhj.2001.2889
14. Coutinho T, Goel K, Corrêa de Sá D, Kragelund C, Kanaya AM, Zeller M, et al. Central Obesity and Survival in Subjects With Coronary Artery Disease. Journal of the American College of Cardiology. 2011;57(19):1877-1886. doi: 10.1016/j.jacc.2010.11.058
15. Arnlov J, Ingelsson E, Sundstrom J, Lind L. Impact of Body Mass Index and the Metabolic Syndrome on the Risk of Cardiovascular Disease and Death in Middle-Aged Men. Circulation. 2009;121(2):230-236. doi: 10.1161/circulationaha.109.887521
16. Thomsen M, Nordestgaard BG. Myocardial Infarction and Ischemic Heart Disease in Overweight and Obesity With and Without Metabolic Syndrome. JAMA Internal Medicine. 2014;174(1):15. doi: 10.1001/jamainternmed.2013.10522
17. Kramer CK, Zinman B, Retnakaran R. Are Metabolically Healthy Overweight and Obesity Benign Conditions? Annals of Internal Medicine. 2013;159(11):758. doi: 10.7326/0003-4819-159-11-201312030-00008
18. Coutinho T, Goel K, Corrêa de Sá D, Carter RE, Hodge DO, Kragelund C, et al. Combining Body Mass Index With Measures of Central Obesity in the Assessment of Mortality in Subjects With Coronary Disease. Journal of the American College of Cardiology. 2013;61(5):553-560. doi: 10.1016/j.jacc.2012.10.035
19. Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. European Heart Journal. 2012;33(13):1635-1701. doi: 10.1093/eurheartj/ehs092
20. Garvey WT, Garber AJ, Mechanick JI, Bray GA, Dagogo-Jack S, Einhorn D, et al. American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the 2014 Advanced Framework for a New Diagnosis of Obesity as a Chronic Disease. Endocrine Practice. 2014;20(9):977-989. doi: 10.4158/ep14280.ps
Review
For citations:
Samorodskaya I.V. The new paradigm of obesity. Problems of Endocrinology. 2014;60(5):43-48. (In Russ.) https://doi.org/10.14341/probl201460543-48
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