The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation
https://doi.org/10.14341/probl201561131-35
Abstract
The objective of the present study was differential diagnostics between ovotestis and gonadal dysgenesis, the choice of the gender and the surgical strategy for the treatment of abnormal sexual glands. Diagnostics of the disturbances of gonadal differentiation (DGD) requires morphological verification. The ovotesticular gonad is characterized by the presence of a mature ovarian tissue and a dysgenetic testicular component. The authors describe the surgical separation of the ovotestis with preservation of the segments represented by the mature ovarian tissue. The presence of immature ovarian elements in the testicular gonad is one of the signs of its dysgenesis. Such cases need to be treated by the surgical removal of dysgenetic gonads.
About the Authors
D A Morozov
Research Centre of Children’s Health, Moscow; I.M. Sechenov First Moscow State Medical University, Moscow
MD, PhD, Professor
MD, PhD, Professor
N Yu Raygorodskaya
V.I. Razumovsky Saratov State Medical University, Saratov
MD, PhD
MD, PhD
N V Bolotova
V.I. Razumovsky Saratov State Medical University, Saratov
MD, PhD, Professor
MD, PhD, Professor
E S Pimenova
Research Centre of Children’s Health, Moscow; I.M. Sechenov First Moscow State Medical University, Moscow
MD, PhD
MD, PhD
G N Maslyakova
V.I. Razumovsky Saratov State Medical University, Saratov
MD, PhD, Professor
MD, PhD, Professor
E N Tsmokalyuk
V.I. Razumovsky Saratov State Medical University, Saratov
MD, PhD
MD, PhD
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Review
For citations:
Morozov D.A., Raygorodskaya N.Yu., Bolotova N.V., Pimenova E.S., Maslyakova G.N., Tsmokalyuk E.N. The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation. Problems of Endocrinology. 2015;61(1):31-35. (In Russ.) https://doi.org/10.14341/probl201561131-35
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