Prospects for designing Russian gene engineering agents for medicine. Rastan is the first Russian recombinant human growth hormone
https://doi.org/10.14341/probl200753219-24
Abstract
The development of modern pharmacology cannot be imagined without the use of genetic engineering methods (recombinant DNA technology). The success of medicine is increasingly based on the active use of protein preparations obtained using the technology of transferring hereditary information (genes) from one organism to another.
The emergence of the ability to express foreign genes in the cells of various organisms (both eukaryotes and prokaryotes) has become one of the revolutionary events in the science of the last two decades of the 20th century and laid the foundations of modern biotechnology.
About the Authors
A. G. GabibovShemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
N. A. Ponomarenko
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
I. I. Vorobyev
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
D. I. Bairamashvili
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
V. D. Knorre
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
A. M. Shuster
Masterklon Ltd.
Russian Federation
V. A. Martyanov
Masterklon Ltd.
Russian Federation
I. K. Krylov
PJSC Pharmstandard
Russian Federation
V. A. Burmistrov
PJSC Pharmstandard
Russian Federation
I. I. Dedov
Endocrinology Research Centre
Russian Federation
A. I. Miroshnikov
Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences
Russian Federation
References
1. Баирамашвили Д. И. // Рос. хим. журн. - 2005. - Т. 49, № 1.-С. 34-45.
2. Воробьев И. И., Пономаренко Н. А., Александрова Е. С. и др. // Биотехнология. - 2005. - № 5. - С. 44-48.
3. Габибов А. Г., Пономаренко Н. А., Воробьев И. И. и др. Рскомбинантная плазмидная ДНК pESl-6, кодирующая полипептид соматотропин, и штамм Escherichia coli BL21(DE3)/pESl-6-пpoдyцeнт рекомбинантного соматотропина. - Пат. 2233879 РФ, 2004.
4. Гусаров Д. А., Востриков В. В., Ручко Е. А., Баирамашвили Д. И. // Биотехнология. - 2006. - № 2. - С. 44-49.
5. Патрушев Л. И., Баирамашвили Д. И., Мирошников А. И. Штамм бактерий Escherichia coli BL-07 - продуцент проинсулина человека. - Пат. 2267534 РФ, 2006.
6. Chen G. Q., Gоиаих Е. // Ргос. Natl. Acad. Sci. USA. - 1997. - Vol. 94, N 25. - P. 13431-13436.
7. Clark A. J., Adeniyi-Jones R. O., Knight G. et al. // Lancet. - 1982. - Vol. 2, N 8294. - P. 354-357.
8. Cronin M. J. // J. Pediatr. - 1997. - Vol. 131, N I, Pt 2. - P. S5-S7.
9. Darendeliler F., Hindmarsh P. C., Brook С. G. // Horm. Res. -1990. - Vol. 33, N 2-4. - P. 128-136.
10. Kaplan S. L., Underwood L. E., August G. P. et al. // Lancet. -1986. - Vol. 1, N 8483. - P. 697-700.
11. Le H. V., Trotta P. P. // Bioprocess Technol. - 1991. - Vol. 12.-P. 163-181.
12. Lombardi G., Colao A., Ferone D. et al. // Horm. Res. - 1997. -Vol. 48. - Suppl 4. - P. 38-42.
13. Low J. F., Herndon D. N., Barrow R. E. II Lancet. - 1999. - Vol. 354, N 9192. - P. 1789.
14. Rader R. A. // Biopharmaceutical products in the US Europe an markets. 5-th ed. Rockwill, 2005.
15. Schmetzer O., Moldenhauer G., Riesenberg R. et al. // J. Immunol. - 2005. - Vol. 174, N 2. - P. 942-952.
16. Vimраni G. V., Vimpani A. F., Lidgard G. P. et al. // Br. Med. J. - 1977. - Vol. 2, N 6084. - P. 427-430.
Review
For citations:
Gabibov A.G., Ponomarenko N.A., Vorobyev I.I., Bairamashvili D.I., Knorre V.D., Shuster A.M., Martyanov V.A., Krylov I.K., Burmistrov V.A., Dedov I.I., Miroshnikov A.I. Prospects for designing Russian gene engineering agents for medicine. Rastan is the first Russian recombinant human growth hormone. Problems of Endocrinology. 2007;53(2):19-24. (In Russ.) https://doi.org/10.14341/probl200753219-24
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