The blood concentrations of testosterone, dehydroepiandrosterone sulfate and free androgen index in women with hirsutism
https://doi.org/10.14341/probl200854242-46
Abstract
Hyperandrogenism is a commonest endocrine disorder in women of reproductive age and a cause of many metabolic diseases. The purpose of this study was to measure the blood levels of androgens in women with hirsutism (Ferriman-Gallwey scale > 8 scores) and to reveal the most informative marker of hyperandrogenism in hirsutism. A hundred forty-nine women aged 18-35 years who complained about hirsutism were examined. The women with hirsitism (Ferriman-Gallwey scale > 8 scores) were observed to have statistically significantly elevated serum levels of total testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin and the high free androgen index (p < 0.001). The increased free androgen index (54.8%) was more frequently detected in hirsutism. This study showed that hirsutism was doubtlessly associated with the elevated serum content of androgens; however, even 34.4% of the females had normal blood leveb of androgens.
About the Authors
D. KozlovieneKaunas University of Medicine
Lithuania
G. Kazanavicius
Kaunas University of Medicine
Lithuania
V. Kruminis
Kaunas University of Medicine
Lithuania
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Review
For citations:
Kozloviene D., Kazanavicius G., Kruminis V. The blood concentrations of testosterone, dehydroepiandrosterone sulfate and free androgen index in women with hirsutism. Problems of Endocrinology. 2008;54(2):42-46. (In Russ.) https://doi.org/10.14341/probl200854242-46

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