The diagnostic accuracy of fine-needle biopsy of the thyroid under ultra-sound guidance and the morphological structure of nodular goiter in children and adolescents
https://doi.org/10.14341/probl200854516-20
Abstract
In 2000 to 2007, fine-needle biopsy (FNB) of the thyroid was made under ultrasound guidance in 202 children and adolescents (35 boys and 167 girls) aged 7.2 to 17.7 years (median 15.6 years). Cytological specimens proved to be of informative value in 20(9.9%) cases. If the size of nodules was less than 10 mm, the frequency of informative biopsies was significantly lower than if the size was 1 cm or more (63.2% versus 94.9%; х2 = 23.23; p = 0.000). Forty-one patients were operated on for thyroid cancer (n = 21), follicular adenoma (n - 15), and colloidal goiter (n = 5). The proportion of thyroid cancer in the morphological pattern of nodular goiter was 11.5% (21 of 182 informative FNBs). The high accuracy of FNB under ultrasound guidance in the diagnosis of thyroid tumors (97.2% sensitivity, 80% specificity, 95.1% accuracy) determines adequate treatment policy against thyroid nodules in children and adolescents.
About the Authors
A. V. Kiyaev
Regional Children's Clinical Hospital № 1
Russian Federation
Russian Federation
N. A. Yeliseyeva
Regional Children's Clinical Hospital № 1
Russian Federation
Russian Federation
N. P. Koroleva
Regional Children's Clinical Hospital № 1
Russian Federation
Russian Federation
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Review
For citations:
Kiyaev A.V., Yeliseyeva N.A., Koroleva N.P. The diagnostic accuracy of fine-needle biopsy of the thyroid under ultra-sound guidance and the morphological structure of nodular goiter in children and adolescents. Problems of Endocrinology. 2008;54(5):16-20. (In Russ.) https://doi.org/10.14341/probl200854516-20
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