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The levels of thyroid hormones in hemorrhagic stroke

https://doi.org/10.14341/probl200955415-20

Abstract

Radioimmunoassay using was used to study the blood concentrations of thyroid hormones (thyroid-stimulating hormone (TSH), T3, and T4) in patients with hemorrhagic stroke as intracerebral hematoma. The authors analyzed two patient groups: 1) those operated on for intracerebral hematoma removal; 2) those receiving medical treatment. Surgical intervention resulted in local fibrinolysis of a hematoma remnant. The level of thyroid hormones was studied over time from the 1st day to the 28th day of therapy. Each group was then divided into 2 subgroups: survivors and dead patients. Mortality group was 77.2% in the medical treatment group and 17.2% in the surgical treatment group. The performed studies established elevated concentrations in cases of good outcome of stroke. All the patients were found to have low T3 concentrations that were more pronounced in patients with a poor outcome. The level of T4 did not differ from the control values in patients with good results. Hematoma removal contributed to an increase in the concentrations of TSH and triiodothyronine

About the Authors

A V Elfimov

Yaroslavl State Medical Academy


Russian Federation


N N Spirin

Yaroslavl State Medical Academy


Russian Federation


A D Nozdrachev

Saint Petersburg State University


Russian Federation


M M Fateev

Yaroslavl State Medical Academy


Russian Federation


A. O. Ivanov

Yaroslavl State Medical Academy


Russian Federation


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Review

For citations:


Elfimov A.V., Spirin N.N., Nozdrachev A.D., Fateev M.M., Ivanov A.O. The levels of thyroid hormones in hemorrhagic stroke. Problems of Endocrinology. 2009;55(4):15-20. (In Russ.) https://doi.org/10.14341/probl200955415-20

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