The role of atrial natriuretic peptide in the development of arterial hypertension in patients with hypothalamic puberty syndrome
https://doi.org/10.14341/probl199743421-22
Abstract
Fifty-two youths with the hypothalamic syndrome of puberty and 13 normal subjects aged 13 to 24 were examined in order to elucidate the contribution of the depressor system factor atrial natriuretic peptide (ANP) to the development of arterial hypertension in such patients. The disease standing was 2 to 11 years. Plasma ANP, plasma renin activity, and serum aldosterone were radioimmunoassayed. The level of ANP was reliably decreased in patients with borderline arterial hypertension and directly correlated with changes of the renin-aldosterone system. This permitted a conclusion on the insufficient role of the depressor system in patients with the pubertal hypothalamic syndrome and contribution of ANP to the development of arterial hypertension and of disorders in the functional relationships between the renin-aldosterone system and ANP.
About the Authors
T. P. KrivchenkoSamara Medical University
Russian Federation
N. I. Verbovaya
Samara Medical University
Russian Federation
References
1. Вербовая Н. И., Гуляев Н. Н., Лоткова Е. А., Затулина М. В. Пубертатно-юношеский диспитуитаризм, особенности клиники, диагностики: Метод, рекомендации. — Куйбышев, 1985.
2. Гапон Л. И., Шафер М. Ж., Велижанина И. А., Журавлева Т. Д. // Тер. арх. — 1990. — № 12. — С. 40—44.
3. Лоткова Е. А. Прессорные факторы и функция почек при пубертатно-юношеском диспитуитаризме: Дис. ... канд. мед. наук. — Самара, 1987.
4. Постнов А. Ю. Морфофункциональное изучение ПНФ при экспериментальных моделях первичной и вторичной гипертензии: Дис. ... канд. мед. наук. — М., 1990.
5. Сургучев А. П., Григорьянц Р. А., Ураков В. Н. // Тер. арх. - 1987. - № 5. - С. 142-144.
6. Терещенко И. В. Эндокринные расстройства у юношей и девушек в пубертатном периоде. — М., 1991.
7. Arendt R. М., Gerber A. S. et al. // J. Hypertens. — 1986. — Vol. 4, N 2. - P. 131-135.
8. Atlas S. A., Kleinnest H. // Nature. — 1984. — Vol. 309. — P. 716-719.
9. Atlas S. A. // Rec. Prog. Horm. Res. — 1986. — Vol. 42. — P. 222-249.
10. Blaine E. H. // Clin. Exp. Thory. Prac. — 1985. — Vol. A7, N 5. - P. 839-850.
11. De Bold A. S., De Bold M. I., Sarda Y. R. // J. Hypertens. — 1986. - Vol. 4, N 2. - P. 3-7.
12. Hedner T., Hedner I. et al. // J. cardiovasc. Pharmacol. — 1986. - N 8. - P. 1299.
13. Marin—Gres M., Fleming S. T. et al. // Nature. — 1986. — Vol. 3, N 24. - P. 473-476.
14. Montorsi P., Tonolo G. et al. // Hypertension. — 1987. — Vol. 10, N 6. - P. 570-576.
15. Rubin S. A., Levin E. R. // J. clin. Endocrinol. Metab. — 1992 - Vol. 78, N 2. P. 6-10.
16. Vuoltenaho O. // Res. Comm. — 1985. — Vol. 120, N I.- P. 82-88.
17. Wilbert M. T, Sanssen A. M. et al. // Hypertension. — 1992. — Vol. 20. - P. 80-84.
Review
For citations:
Krivchenko T.P., Verbovaya N.I. The role of atrial natriuretic peptide in the development of arterial hypertension in patients with hypothalamic puberty syndrome. Problems of Endocrinology. 1997;43(4):21-22. (In Russ.) https://doi.org/10.14341/probl199743421-22
Views:
1552
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).
Email this article 
.jpg){kind=logo}
