The dynamics of thyroid hormones in rats when modeling polycystic ovary syndrome
https://doi.org/10.14341/probl199844333-35
Abstract
The time course of triiodothyronine, thyroxine, and progesterone is followed up in albino rats with polycystic ovaries developing after postnatal androgenization of newborn females. Serum and plasma hormones were measured by competitive immunoassay based on intensified fluorescence. Serum and plasma T3 and T4 levels in rats with polycystic ovaries during the period corresponding to sexual maturation were higher than in normal animals. In adult rats T3 levels in the experimental and control animals leveled, but T4 content was decreased in androgen-treated animals. Progesterone level in health was notably higher than in animals with polycystic ovaries at all stages of postnatal ontogenesis.
About the Authors
S. N. SmirnovaCrimean Medical Institute
Ukraine
M. F. Romashova
Crimean Medical Institute
Ukraine
A. V. Antonichev
Crimean Medical Institute
Ukraine
V. A. Korolev
Crimean Medical Institute
Ukraine
References
1. Бондаренко В. В. Реактивно-деструктивные и репаративные процессы овариальной железы млекопитающих в норме и при применении гомеостаза в системе репродукции: Автореф. дис. ... канд. биол. наук. — Симферополь, 1992.
2. Гончаров Н. П., Крымин В. В. // Пробл. эндокринол. — 1992. -№ 5. - С. 17-19.
3. Королев В. А., Ромашова М. Ф., Лазарев К. Л. Актуальш питания морфологи. — Ивано-Франковськ, 1994. — С. 88.
4. Резников А. Г., Демкин Л. П., Носенко Н. Д. // Пробл. эндокринол. — 1976. — № 6. — С. 71—76.
5. Ромашова М. Ф., Королев В. А., Лазарев К. Л. // Конференция морфологов. — Черновцы, 1996. — С. 277—278.
6. Шакаева Ф. В., Коренева Г. П. // Акуш. и гин. — 1986. — № 5. - С. 26-27.
7. Эндокринно-гинекологическая патология в практике терапевта / Под ред. С. А. Шадрина. — Свердловск, 1991.
8. Whitehead Т. et al. // Nature. - 1983. - Vol. 305. - P. 158-160.
Review
For citations:
Smirnova S.N., Romashova M.F., Antonichev A.V., Korolev V.A. The dynamics of thyroid hormones in rats when modeling polycystic ovary syndrome. Problems of Endocrinology. 1998;44(3):33-35. (In Russ.) https://doi.org/10.14341/probl199844333-35
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