Prevention and treatment of diabetic microangiopathy: A lecture
https://doi.org/10.14341/probl11491
Abstract
One of the main complications leading to high disability and mortality in patients with diabetes mellitus is atherosclerotic vascular disease (diabetic macroangiopathy). At the same time, the frequency of atherosclerosis among patients with diabetes mellitus is significantly affected by the so-called risk factors for atherosclerosis. In particular, the incidence of atherosclerosis among the general population and among diabetics increases with increased levels of cholesterol (cholesterol) in the blood, blood pressure, smoking and obesity. However, in patients with diabetes mellitus, mortality, for example, from coronary heart disease increases by 3 times against any of the known risk factors. But even without risk factors, the frequency of atherosclerotic vascular damage in patients with diabetes is much higher than in non-diabetic patients, i.e. diabetes in itself is a risk factor for atherosclerosis.
References
1. Богацкая Л. Н., Киряков А., Коркушко О. В. и др. // Вопр. геронтол. — 1990. — № 12. — С. 22—27.
2. Качарова А. Г., Тертое В. В., Жукова И. М., Орехова А. Н. // Кардиология. — 1992. — № 6. — С. 21—23.
3. Кухарчук В. В., Кошечкин В. А. и др. // Кардиология. — 1990. — № 12. — С. 16—18.
4. Локшина Л. И., Тананова Г. В., Майоров В. Н. и др. // Сов. мед. — 1986. — № 5. — С. 67—69.
5. Betteridge D. J. // Diabet. Med. — 1989. — Vol. 6. — P.195— 218. ‘
6. Conner P. L, Berge K. G., Wenger N. K. et al. // J. Amer. Coll. Cardiol. — 1986. — Vol. 8. — P. 1245—1255.
7. Carew T. Е., Schwenke D. C., Steiberg D. // Prog. nat. Acad. Sei. USA. — 1987. — Vol. 84. — P. 7725—7729.
8. Frick M. N., Elo O., Haapa K. et al. // New Engl. J. Med. — 1987. — Vol. 317. — P. 1237—1245.
9. Garg A., Grandy S. M. // Diabetes. — 1989. — Vol. 38. — P. 364—372.
10. Grundy S. M. // Hypercholesterolemia and Atherosclerosis. Pathogenesis and Prevention / Eds D. Steinberg, J. M. Olefsky. — New York, 1987. — P. 169—193.
11. Hirch J., Salzman Е. W., Harker L. et al. // Chest. — 1989. — Vol. 95. — P 12S—18S.
12. Leaf A., Weber P. C. // New Engl. J. Med. — 1988. — Vol. 318. — P. 549—557.
13. Lipid Research Clinics Programme. The Research Coronary Primary Prevention Trial. Results I and II // J. Amer. med. Assoc. — 1984. — Vol. 1251. — P. 351—374.
14. Pyorala K., Laakso M., Uusitupa M. // Diabetes / Metabol. Rev. — 1987. — Vol. 3. — P. 463—524.
15. Stomier J. // Diabet. Care. — 1989. — Vol. 12. — P. 573—579.
16. Study group of the European Atherosclerosis Society. Strategies for the prevention of coronary heart disease, a policy statement of the European Atherosclerosis Society // Europ. Heart J. — 1987. — Vol. 8. — P. 77—88.
Review
For citations:
Dreval A.K. Prevention and treatment of diabetic microangiopathy: A lecture. Problems of Endocrinology. 1995;41(6):29-34. (In Russ.) https://doi.org/10.14341/probl11491

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).