Morphology of the thyroid tissue in multinodular euthyroid goiter

Abstract

Multinodular euthyroid goiter is a disease characterized by the presence of two or more nodes that can be located in one or both lobes of the thyroid gland, and, as a rule, not accompanied by a dysfunction of the latter. Currently, the most common treatment for patients with this pathology is the surgical removal of nodes. However, the volume of surgical intervention for multinodular euthyroid goiter refers to the unresolved problems of surgical endocrinology. On the one hand, after radical operations, a significant number of patients have postoperative hypothyroidism, on the other hand, with less radical operations, a relapse occurs. At the same time, there is a point of view that negates the dependence of disease recurrence on the volume of surgery.

Our observations indicate that with multinodular euthyroid goiter, focal goiter changes are observed in the surrounding thyroid tissue nodes, often with a tendency to nodule formation. In this regard, we set ourselves the goal of studying the morphological features of the structure of resected thyroid tissue in patients with multinodular euthyroid goiter, paying particular attention to the structure of the nodes and to the state of the thyroid tissue outside them. In addition, an attempt was made to establish the dependence of the development of postoperative hypothyroidism and / or relapse of the disease on the amount of left thyroid tissue.