Reproductive function in men - participants in the aftermath of the Chernobyl accident
https://doi.org/10.14341/probl11569
Abstract
Endocrine parameters and spermatogenesis values were assessed in 328 men aged 25-45 years who participated in liquidation of the Chernobyl aftermath and in 88 age-matched healthy controls. The mean radiation dose in liquidators was 0.16+0.006 Gy. LH, FSH, prolactin, testosterone, and hydrocortisone were radioimmunoassayed using standard WHO reagents. Spermograms were analyzed according to WHO recommendations (1992). The mean hormone levels in the blood of liquidators were within the normal range and did not differ from those in the controls. Individual deviations in hormone content did not correlate with radiation dose and their incidence was compatible with that in the control group. The most frequent disorders of spermatogenesis in the liquidators were teratospermia (29%) and oligospermia (23%). Spermogram abnormalities did not depend on the absorbed dose. Thus, there are no appreciable shifts in the mechanisms of endocrine regulation of the reproductive function and in spermatogenesis 7-9 years after radiation exposure.
About the Authors
N. P. GoncharovEndocrinology Research Center RAMS
Russian Federation
G. V. Katsiya
Endocrinology Research Center RAMS
Russian Federation
G. S. Kolesnikova
Endocrinology Research Center RAMS
Russian Federation
A. D. Dobracheva
Endocrinology Research Center RAMS
Russian Federation
T. N. Todua
Endocrinology Research Center RAMS
Russian Federation
V. V. Vaks
Endocrinology Research Center RAMS
Russian Federation
E. I. Marova
Endocrinology Research Center RAMS
Russian Federation
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Review
For citations:
Goncharov N.P., Katsiya G.V., Kolesnikova G.S., Dobracheva A.D., Todua T.N., Vaks V.V., Marova E.I. Reproductive function in men - participants in the aftermath of the Chernobyl accident. Problems of Endocrinology. 1998;44(4):25-28. (In Russ.) https://doi.org/10.14341/probl11569
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