Prolactin-secretory function of the pituitary after hypotonic hemorrhage and lactation
https://doi.org/10.14341/probl11599
Abstract
Relationship between blood loss in labor and pituitary prolactin secretory function was studied in 157 puerperants, 51 of these with blood loss of 0.5-0.7% body weight (group 1), 49 with blood loss of 0.71-1.2% b. w. (group 2), 27 with massive blood loss of more than 1.2% b. w. (group 3), and 30 healthy puerperae with normal blood loss (controls).
The results indicate that the higher was blood loss, the more marked was drop in the blood prolactin level. Hypoprolactinemia led to a decrease in breast milk volume. The incidence of hypogalactia was 37.3% in group 1, 67.3% in group 2, and 88.9% in group 3.
Adequate infusion therapy in the postpartum period, aimed at restoration of circulating blood volume, had a favorable impact on prolactin secretion. When circulating blood volume was not restored completely, a decrease in the breast milk volume was observed in parallel with a decrease in the serum prolactin concentration.
Hence, the pituitary prolactin secretory function deteriorates after severe blood loss in labor; adequate infusion therapy prevents the risk of hypogalactia.
About the Authors
T. Kh.-M. KhashaevaDagestan Medical Academy
Russian Federation
A. A. Arslanbekova
Dagestan Medical Academy
Russian Federation
N. S.-M. Omarov
Dagestan Medical Academy
Russian Federation
Z. A. Abusueva
Dagestan Medical Academy
Russian Federation
References
1. Айламазян Э. К. Неотложная помощь при экстремальных состояниях в акушерской практике. - Н. Новгород, 1997.
2. Алипов В. И., Колодина Л. Н., Корхов В. В. Лактация женщины. - Ашхабад, 1988.
3. Мазурин А. В. // БМЭ. - М., 1977. - Т. 6. - С. 464-467.
4. Масоба П., Ререкин И. А. // IX съезд акушеров-гинекологов УССР. - Киев, 1991. - С. 256-258.
5. Мясникова Г. П. Эндокринная система женщин после родов, осложненных массивной кровопотерей: Автореф. дис. ... д-ра мед. наук. - Л., 1988.
6. Рагимова Ш. А. // Физиология человека. - 1991. - № 6. - С. 126-132.
7. Репина М. А. Кровотечения в акушерской практике. - М., 1986.
8. Серов В. Н., Стрижаков А. Н., Маркин С. А. Руководство по практическому акушерству. - М., 1997.
9. Синимяэ X. В. // Тезисы XIII конференции эндокринологов Эстонии. - Тарту, 1990. - С. 147.
10. Beadry М., Fufour R., Marcoux S. // S. Rediats. - 1995. - Vol. 126. - P. 191-197.
11. Kent J. C., Arthur P. G., Retallack R. W. // J. Dairy Res. - 1992. - Vol. 59, N 2. - P. 161-167.
12. Perez A., Labbor M. H., Guenan J. T. // Lancet. - 1992. - Vol. 339, N 4. - P. 968-970.
13. Roqan W. J., Gladen В. C. // Early Hum. Dev. - 1993. - Vol. 31. - P. 181-193.
Review
For citations:
Khashaeva T.Kh., Arslanbekova A.A., Omarov N.S., Abusueva Z.A. Prolactin-secretory function of the pituitary after hypotonic hemorrhage and lactation. Problems of Endocrinology. 2002;48(3):10-13. (In Russ.) https://doi.org/10.14341/probl11599
Views:
1111
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).
Email this article 
.jpg){kind=logo}
