Comparison of bone mineral density measurements in patients with endocrinopathies

Abstract

Mineral bone density (MBD) was estimated in 25 patients with chronic adrenal insufficiency (CAI), 38 with diffuse toxic goiter (DTG), and 37 with hyperprolactinemic hypogonadism (HH), by using quantitative computed tomography (QCT) and double-energy X-ray ab­sorption study (DEXA). Analyzing the findings have led to the conclusion that to estimate MBD, it is sufficient to examine the bones containing the high levels of spongy substance in patients with CAI, by using QCT or DEXA, and the skeletal regions that consist of both trabecular and cortical tissue in patients with DTG, DEXA being more suitable for these purposes. In females with HH, MBD should be measured in the skeletal regions, which mainly consists of spongy substance, as well as in their study, preference should be given to QCT.