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Magnetic resonance images in the diagnosis of pathology of hypothalamic-pituitary system in Itsenko-Cushing's disease

https://doi.org/10.14341/probl11640

Abstract

At the background of the complex clinical, hormonal and instrumental examination of 96 patients with diagnosis of Itsenko-Cushing’s disease the detailed analysis of MR tomographic picture and study of the clinical status in dependence on structural changes of the pituitary were carried out. MRI-examination revealed different pituitary pathology in 91,7% of patients with Cushing’s disease: in 7,3%o of cases the polymorphous adenohypophysis structure was detected, in 6,2% of cases the picture of empty sella turcica was disclosed, in 78%> of patients there was found pituitary adenoma, including microadenoma in 58,3%> of cases and macroadenoma- in 19,8%> of patients. The analysis did not show any correlation between sizes and corticotropinoma features discovered by MRI-examination and its hormonal activity.

About the Authors

I. I. Dedov

Endocrinology Research Center of RAMS


Russian Federation


A. V. Vorontsov

Endocrinology Research Center of RAMS


Russian Federation


Ye. I. Marova

Endocrinology Research Center of RAMS


Russian Federation


L. V. Belchenko

Endocrinology Research Center of RAMS


Russian Federation


Ye. V. Averkieva

Endocrinology Research Center of RAMS


Russian Federation


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Review

For citations:


Dedov I.I., Vorontsov A.V., Marova Ye.I., Belchenko L.V., Averkieva Ye.V. Magnetic resonance images in the diagnosis of pathology of hypothalamic-pituitary system in Itsenko-Cushing's disease. Problems of Endocrinology. 2002;48(5):22-29. (In Russ.) https://doi.org/10.14341/probl11640

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)