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Transient neonatal hypothyroidism: Children’s history of thyroid status

https://doi.org/10.14341/probl11739

Abstract

The paper deals with evaluation of the follow-up of the thyroid status in children with prior transient neonatal hypothyroidism (TNH). Under examination were 42 children aged 5-7 years, born in Moscow, who had, according to the screening for congenital hypothyroidism, a thyroid-stimulating hormone level (TSH-1) of > 20 mU/l which spontaneously became normal by the moment of re- or serum testing. A control group comprised children (n = 21) who had normal birth TSH levels and were on a par with all signs. The findings indicate that the children with prior TNH are a group at risk for thyroid insufficiency and are to be followed up. The revealed features of the size and structure of the thyroid in children with prior TNH (thyroid volume was equal to and below 10 percentiles in 19% of cases and malformations were encountered in every 5 patients) could exert a negative effect on the functional activity of the hypothalamus-pitu- itary-thyroid system in neonatality.

About the Authors

Ye. V. Kiseleva

Russian Medical Academy of Postgraduate Education


Russian Federation


L. N. Samsonova

Russian Medical Academy of Postgraduate Education


Russian Federation


G. V. Ibragimova

Russian Medical Academy of Postgraduate Education


Russian Federation


A. V. Ryabykh

Russian Medical Academy of Postgraduate Education


Russian Federation


E. P. Kasatkina

Russian Medical Academy of Postgraduate Education


Russian Federation


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Review

For citations:


Kiseleva Ye.V., Samsonova L.N., Ibragimova G.V., Ryabykh A.V., Kasatkina E.P. Transient neonatal hypothyroidism: Children’s history of thyroid status. Problems of Endocrinology. 2003;49(5):30-32. (In Russ.) https://doi.org/10.14341/probl11739

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)