Comparative assessment of the effects of glurenorm and some sulfonylurea preparations on microcirculation in type II diabetes mellitus
https://doi.org/10.14341/probl11940
Abstract
Analysis of the effects of glurenorm and some sulfonylurea drugs, such as maninil, minidiab, chlorpropamid, on some parameters of intravascular microcirculation has demonstrated the specific features of this drug. Though all these hypoglycemic agents favorably influence the microcirculation when carbohydrate metabolism compensation is attained, glurenorm improved the status of formed elements of the blood (red cell and platelet aggregation) more noticeably than the rest drugs, which fact recommends it as a drug of choice for patients with type II medium-severe diabetes with the predominant involvement of the cellular component of the microcirculation.
About the Authors
I. M. KakhnovskyMoscow medical Academy named after I. M. Sechenov
Russian Federation
T. V. Koroleva
Moscow medical Academy named after I. M. Sechenov
Russian Federation
V. N. Zakharchenko
Moscow medical Academy named after I. M. Sechenov
Russian Federation
S. N. Larionov
Moscow medical Academy named after I. M. Sechenov
Russian Federation
References
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Review
For citations:
Kakhnovsky I.M., Koroleva T.V., Zakharchenko V.N., Larionov S.N. Comparative assessment of the effects of glurenorm and some sulfonylurea preparations on microcirculation in type II diabetes mellitus. Problems of Endocrinology. 1993;39(2):7-9. (In Russ.) https://doi.org/10.14341/probl11940
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