Age-specific features of dopaminergic regulation of prolatin secretion in men
https://doi.org/10.14341/probl11966
Abstract
Age-specific time course of prolactin secretion and features of dopaminergic regulation of this hormone secretion were studied in boys aged 3 to 15 and in adult men aged 20 to 25. Blood plasma prolactin concentration was found reduced in boys, and this hormone level, characteristic for adults, sets up at the age of 9-11. Dopaminergic regulation of prolactin secretion undergoes, three stages in boys: Stage 1 — hyperreaction to introduction of a receptor antagonist at the age of 3 to 8, Stage 2 — at the age of 9 to 11 — reduced reaction to D2 receptor blocking, though this reaction being much higher than in adults, and Stage 3 (at the age of 12-15) — development of a normal reaction characteristic of adults.
About the Authors
Ye. Ye. Gubernatorov
Endocrinology research centre of RAMS
Russian Federation
Russian Federation
G. A. Gherasimov
Endocrinology research centre of RAMS
Russian Federation
Russian Federation
V. P. Vershinsky
Endocrinology research centre of RAMS
Russian Federation
Russian Federation
S. A. Pivovarov
Endocrinology research centre of RAMS
К. V. Orlov
Endocrinology research centre of RAMS
Russian Federation
Russian Federation
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Review
For citations:
Gubernatorov Ye.Ye., Gherasimov G.A., Vershinsky V.P., Pivovarov S.A., Orlov К.V. Age-specific features of dopaminergic regulation of prolatin secretion in men. Problems of Endocrinology. 1993;39(2):22-24. (In Russ.) https://doi.org/10.14341/probl11966
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