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Analysis of melatonin concentration and its correlation with ovarian disfunction among obese women of reproductive age

https://doi.org/10.14341/probl12710

Abstract

One of the new directions in the study of reproductive disorders in obese women is the effect and receptor sensitivity of  melatonin on the gonadotropic function of the pituitary gland and ovariogenesis, taking into account the chronology of «light pollution». At the present stage, there is very little literature on the influence of the aspects of «light pollution» on the problem of obesity and reproductive disorders in the literature. This review is an attempt to combine the above problem in terms of the impact of «light pollution» and the level of receptor sensitivity of melatonin in women of reproductive age with obesity. The literature search was carried out in Russian (eLibrary, CyberLeninka.ru) and international (PubMed, Cochrane Library) databases in Russian and English. Free access to the full text of the articles was a priority. The selection of sources was prioritized for the period from 2015 to 2019. However, given the insufficient knowledge of the chosen topic, the choice of sources was dated from 1992. The work was carried out as part of the study «Central and peripheral pathophysiological mechanisms of development of adipose tissue diseases, taking into account clinical and hormonal characteristics» 2020–2022.

About the Authors

R. K. Mikheev
Endocrinology Research Centre

Robert K. Mikheev, resident student

Moscow

eLibrary SPIN: 9767-8468


E. N. Andreeva
Endocrinology Research Centre; Moscow State University of Medicine and Dentistry

Elena N. Andreeva, MD, PhD, DSc

Moscow

eLibrary SPIN: 1239-2937


E. V. Sheremetyeva
Endocrinology Research Centre

Ekaterina V. Sheremetyeva, MD, PhD

Moscow

eLibrary SPIN: 9413-5136


Yu. S. Absatarova
Endocrinology Research Centre

Yulia S. Absatarova, MD, PhD

11 Dm. Ulyanov str., Moscow, 117036, Moscow

eLibrary SPIN: 2220-9464


T. A. Ponomareva
Endocrinology Research Centre

Tatyana A. Ponomareva, MD

Moscow

eLibrary SPIN: 1739-4134


O. R. Grigoryan
Endocrinology Research Centre

Оlga R. Grigoryan, MD, PhD, DSc

Moscow

eLibrary SPIN: 3060-8242


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Supplementary files

Review

For citations:

Mikheev R.K., Andreeva E.N., Sheremetyeva E.V., Absatarova Yu.S., Ponomareva T.A., Grigoryan O.R. Analysis of melatonin concentration and its correlation with ovarian disfunction among obese women of reproductive age. Problems of Endocrinology. 2021;67(1):69-75. (In Russ.) https://doi.org/10.14341/probl12710

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