The clinical and experimental analysis of ventricular rhythm disturbances in the patients with type 2 diabetes mellitus suffering from diastolic cardiac insufficiency
https://doi.org/10.14341/probl201561221-27
Abstract
The present study was focused on the assessment of electrophysiological, structural, and functional characteristics of the heart associated with ventricular rhythm disturbances in the patients with type 2 diabetes mellitus (DM2) suffering from diastolic cardiac insufficiency. The study involved a total of 128 patients with DM2 and coronary heart disease (CHD) exhibiting signs of functional class I-III chronic cardiac insufficiency and left ventricular ejection fraction over 50%. The patients were divided into three groups. Group 1 (n=55) included patients presenting with left ventricular relaxation. Group 2 (n=44) was comprised of the patients with the pseudo-normal type of diastolic dysfunction. Group 3 (n=29) consisted of the patients with restrictive diastolic dysfunction. The patients of the latter group were characterized by the high frequency of complicated forms of ventricular arrhythmia, such as Grade IV-V ventricular extrasystole (48.3%) and Grade III ventricular extrasystole (34.5%). Restrictive type of diastolic dysfunction was associated with the delayed fragmented activity in the end part of the ventricular complex in 72.4% of the patients. The close correlation between the left ventricular diastolic function and parameters of myocardial electrical remodeling was documented.
About the Authors
I P Tatarchenko
Penza Institute of Advanced Medical Training, Penza
N V Pozdnyakova
Penza Institute of Advanced Medical Training, Penza
A G Denisova
Penza Institute of Advanced Medical Training, Penza
O I Morozova
Penza Institute of Advanced Medical Training, Penza
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Review
For citations:
Tatarchenko I.P., Pozdnyakova N.V., Denisova A.G., Morozova O.I. The clinical and experimental analysis of ventricular rhythm disturbances in the patients with type 2 diabetes mellitus suffering from diastolic cardiac insufficiency. Problems of Endocrinology. 2015;61(2):21-27. (In Russ.) https://doi.org/10.14341/probl201561221-27
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