Assessment of the severity of iodine deficiency in the Krasnoyarsk region

The severity of iodine deficiency is for the first time assessed for the Krasnoyarsk region with consideration for the factors proposed by the WHO. The studies were carried out in three main climatic and geographic territories: Extreme North (beyond the Polar Circle), North, and Central region. The incidence of goiter is assessed from the data of palpations and ultrasonic findings; the median of ioduria and incidence of increased neonatal TTH values (over 5 mU/liter) are analyzed.

Total incidence of goiter according to findings of palpation and ultrasonic examination is 38 and 20.9%, respectively; the median of ioduria is 3.4 \ig/ml for the region, and increased TTH levels are revealed in 38.7% newborns in the region. These results indicate that the Krasnoyarsk region may be referred to territories with moderate iodine deficiency.

The indicators in Northern and Central regions correspond to medium severe iodine deficiency; it was impossible to define the endemic process in the region beyond the Polar Circle, where slight incidence of endemic goiter (8.3% according to ultrasonic examinations) was paralleled by moderate iodine insufficiency (ioduria median 3.9 \ig/ml) and high incidence (38.7%) of increased TTH values. These data do not necessitate obligatory prophylaxis, but should be taken account of in monitoring the efficacy of preventive measures and are interesting for understanding the causes augmenting the severity of iodine deficit.

йодный дефицит, Крайний север, зобная эндемия

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