The frequency of osteopenia and the dynamics of bone resorption in women with type II diabetes mellitus during menopause
https://doi.org/10.14341/probl19994538-10
Abstract
The incidence of osteopenia in women with type 2 diabetes is higher than in the general population only in patients with normal body weight index (BWI). Measurement of biochemical marker of osseous tissue resorption, deoxypyridinolol (DPD), in the urine showed an inverse correlation between DPD level and BWI: the lower BWI, the more severe is bone resorption. Hormone replacing therapy (estrogen-gestagen preparations) had a favorable impact on bone resorption processes in women with type 2 diabetes.
About the Authors
O. R. GrigoryanEndocrinological Research Center of RAMS; RSMU
Russian Federation
T. O. Chernova
Endocrinological Research Center of RAMS; RSMU
Russian Federation
I. P. Meshkova
Endocrinological Research Center of RAMS; RSMU
Russian Federation
V. Ya. Ignatkov
Endocrinological Research Center of RAMS; RSMU
Russian Federation
N. A. Sergeeva
Endocrinological Research Center of RAMS; RSMU
Russian Federation
M. B. Antsiferov
Endocrinological Research Center of RAMS; RSMU
Russian Federation
I. I. Dedov
Endocrinological Research Center of RAMS; RSMU
Russian Federation
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Review
For citations:
Grigoryan O.R., Chernova T.O., Meshkova I.P., Ignatkov V.Ya., Sergeeva N.A., Antsiferov M.B., Dedov I.I. The frequency of osteopenia and the dynamics of bone resorption in women with type II diabetes mellitus during menopause. Problems of Endocrinology. 1999;45(3):8-10. (In Russ.) https://doi.org/10.14341/probl19994538-10
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