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Clinical and morphological characteristics of follicular thyroid tumors in young people living in a territory contaminated with radionuclides

https://doi.org/10.14341/probl20004667-12

Abstract

The paper presents clinicomorphological characteristics of follicular tumors of the thyroid in young persons exposed to low-dose radiation after the Chernobyl accident. Follicular thyroid adenomas were more frequent (89.4%) and follicular cancer less so. Most of the patients were females (89.4%). No correlations were found between morphological structure of the tumors, symptoms, tumor size and thickness of the capsule. Radiodiagnosis showed that the majority of tumors (63.9%) were "cold". 14.9% of cases had multinodular thyroid lesions. Oxyphilic cell composition of the tumor was registered in 14.9% patients. Formation of papillary structures took place in 52.4% of the follicular adenomas. Epidemiological and molecular-genetic studies should be performed to elucidate the role of the radiation factor in induction of morphological changes in thyroid tissue.

About the Authors

A. Yu. Abrosimov

Endocrinology Research Centre


Russian Federation


A. A. Ilin

Medical Radiological Research Center


Russian Federation


P. O. Rumyantsev

Endocrinology Research Centre


Russian Federation


N. V. Severskaya

Medical Radiological Research Center


Russian Federation


N. Yu. Dvinskikh

Medical Radiological Research Center


Russian Federation


O. R. Terent'ev

Medical Radiological Research Center


Russian Federation


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Review

For citations:


Abrosimov A.Yu., Ilin A.A., Rumyantsev P.O., Severskaya N.V., Dvinskikh N.Yu., Terent'ev O.R. Clinical and morphological characteristics of follicular thyroid tumors in young people living in a territory contaminated with radionuclides. Problems of Endocrinology. 2000;46(6):7-12. (In Russ.) https://doi.org/10.14341/probl20004667-12

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