studies in the early diagnosis of Value of noninvasive diabetic angiopathies

Abstract

Eighty-six patients of both sexes (46 males and 40 females) who had type 1 diabetes mellitus (DM1) in the decompensated state were examined. Moderate and severe DM1 were detected in 66 and 20 patients, respectively. The patients' age ranged from 16 to 46 years. The purpose of the study was to improve early diagnosis and to make a differential diagnosis of diabetic and macroangiopathies of the coronary vessels of the heart and the pulmonary arterial system, by using noninvasive (clinical, instrumental examinations, such as echocardiography, phlebography, apex and right ventricular cardiographies, jugular phlebography, oscillography) and immuno-logical studies. The studies yielded definite calculation criteria (the myocardial viability index (MVI) that characterizes subendocardial blood flow and pulmonary pressure). Diabetic coronary microangiopathies may be stated if MVI is more than 1.3 conventional units. The MVI of less than 1.3 conventional units is indicative of diabetic macroangiopathies (coronary heart disease). The calculation values of pulmonary pressure in patients aged above 40 years who had DM1 in the decompensated state were statistically more sig-nificant than those in these patients in the compensated state, which suggested the presence of diabetic macroangiopathies of the pulmonary arterial system. In diabetic patients aged less than 40 years, the difference in these values was insignificant, which may point to the presence of diabetic microangiopathies. This opens up a way to the early treatment of diabetic microangiopathies and to the prevention of diabetic macroangiopathies.