Association of goiter endemic and latent iron deficiency in Western Siberia

Abstract

The purpose of the investigation was to study the prevalence of latent iron deficiency and goiter endemic and their association in prepubertal children in Western Siberia. A total of 2238 prepubertal children (8-12 years) living in 3 subjects of the Tyumen Region were examined in 2005-2006. The classical criteria for Iodine deficiency (ID), such as iodurla, the frequency of goiter at palpation and ultrasonography, were studied. Serum ferritln was determined by enzyme-linked immunosorbent assay using the DRG-Diagnostics ПРОБЛЕМЫ ЭНДОКРИНОЛОГИИ. 2007. Т. 53, № 5. kits (USA). There was normalization of the median ioduria, which was 117,', in the implementation of the ID prevention program in Western Siberia. By taking into account the 2003 WHO standards, the severity of goiter endemic in 2006 is regarded as moderate in the southern districts of the region and as severe in its autonomous areas. In terms of a serum ferritin level of less than 15 a high frequency of latent iron deficiency was found in the everywhere. Hence it follows that the association of the serum ferritin levels with the thyroid volumes is caused by a concomitance of two significant conditions: severe goiter endemic and frequent latent iron deficiency.