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Strontium ranelate (Bivalos): its place in therapy for post-menopasal osteoporosis (analysis of clinical trials)

https://doi.org/10.14341/probl200753549-53

Abstract

Postmenopausal osteoporosis is a progressive systemic disease of the skeleton, characterized by a decrease in bone mass and a violation of the architectonics of bones, accompanied by an increased tendency to fractures. Osteoporosis is an important medical and social problem due to its high prevalence and frequent complications - skeleton bone fractures, which lead to temporary and permanent disability, worsen the quality of life, and increase mortality, especially among the elderly. According to various authors, mortality rates during the 1st year after a femoral neck fracture range from 12 to 40%. In half of the patients who survived after the fracture, the ability to self-care is significantly limited or lost.

About the Authors

E. G. Zotkin

St. Petersburg City Hospital No. 25


Russian Federation

City Rheumatology Center; City center for the prevention of osteoporosis



I. Eger

Clinic of Rheumatology; Institute of Physiotherapeutic Medicine


Switzerland

Osteoporosis Center with Clinical Research Department



S. Blumhardt

Clinic of Rheumatology; Institute of Physiotherapeutic Medicine


Switzerland

Osteoporosis Center with Clinical Research Department



В Jubelhart

Geneva University Hospital


Switzerland

Department of Geriatrics, Rehabilitation and Bone System Diseases



D. Jubelhart

Clinic of Rheumatology; Institute of Physiotherapeutic Medicine


Switzerland

Department of Geriatrics, Rehabilitation and Bone System Diseases



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Review

For citations:


Zotkin E.G., Eger I., Blumhardt S., Jubelhart В., Jubelhart D. Strontium ranelate (Bivalos): its place in therapy for post-menopasal osteoporosis (analysis of clinical trials). Problems of Endocrinology. 2007;53(5):49-53. (In Russ.) https://doi.org/10.14341/probl200753549-53

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)