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Dynamic interphase tensiometry of the urine is a method of early diagnosis of diabetic nephropathy

https://doi.org/10.14341/probl11285

Abstract

Dynamic surface tension (ST) of the urine was studied in 58 diabetics without manifest clinical laboratory symptoms of nephropathy by means of computer tensiometers MRT1 and MRT2 (Lauda, Germany). A significant decrease in ST values in the median and longer surface life spans and of the angle of tensiogram curve inclination was revealed. Changes in ST parameters (<M - 3m) were observed much more often (in 51.7- 75.9% patients) than shifts in urinary concentrations (>M + 3m) of albumin (in 24.1%), p2 microglobulin (in 31%), and fibronectin (in 8.6%). Dynamic interphase tensiometry of the urine can be used for early diagnosis of diabetic nephropathy and monitoring the efficiency of treatment.

About the Authors

O. V. Sinyachenko

Donetsk State Medical University


Ukraine


V. N. Kazakov

Donetsk State Medical University


Ukraine


M. V. Zyablitseva

Donetsk State Medical University


Ukraine


E. D. Yegudina

Donetsk State Medical University


Ukraine


V. B. Fainerman

Donetsk State Medical University


Ukraine


E. D. Yakubenko

Donetsk State Medical University


Ukraine


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Review

For citations:


Sinyachenko O.V., Kazakov V.N., Zyablitseva M.V., Yegudina E.D., Fainerman V.B., Yakubenko E.D. Dynamic interphase tensiometry of the urine is a method of early diagnosis of diabetic nephropathy. Problems of Endocrinology. 2001;47(1):7-8. (In Russ.) https://doi.org/10.14341/probl11285

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)