Involvement of progesterone in thermoregulation disorders in rats treated with complete Freund's adjuvant
https://doi.org/10.14341/probl11419
Abstract
Changes in blood serum progesterone, thyrotropic and thyroid hormone levels in white outbred rats during development of a subfebrile state induced by a single injection of complete Freund's adjuvant containing killed and dried Mycobacteria butyricum were studied. A rise of body temperature in males and females was associated with an increased level of progesterone and a decreased content of thyrotropic and thyroid hormones in the blood. After normalization of body temperature (4 days after drug injection), the content of progesterone did not differ from the baseline level. Hyperthermia arrest by indomethacin failed to appreciably influence the blood level of this hormone.
About the Authors
V. N. GurinInstitute of physiology of the Academy of Sciences of Belarus
Belarus
I. N. Semenenya
Institute of physiology of the Academy of Sciences of Belarus
Belarus
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Review
For citations:
Gurin V.N., Semenenya I.N. Involvement of progesterone in thermoregulation disorders in rats treated with complete Freund's adjuvant. Problems of Endocrinology. 1995;41(3):39-40. (In Russ.) https://doi.org/10.14341/probl11419
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