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Osseous changes in the foot of a diabetic child

https://doi.org/10.14341/probl11474

Abstract

Diabetic osteoarthropathy (DOAP) is a serious complication of diabetes mellitus (DM) and occurs, as a rule, in people over 30 years old. In most cases, DOAP is observed in women with insulin-dependent diabetes and with a disease duration of more than 10 years. The frequency of this complication ranges from 0.2 to 0.5%. DOAP is characterized by a unilateral lesion of the feet. Early clinical symptoms are thickening and erythema of the skin. As the disease progresses, deformations of bones and joints develop. Radiologically in these cases, osteolysis, osteoporosis, bone fragmentation, joint disintegration are determined. A histological examination, as a rule, reveals an increase in osteoclastic activity with bone resorption and proliferation of connective tissue, as well as aseptic vascular necrosis.

About the Authors

O. V Remizov

Endocrinology research center of RAMS


Russian Federation


A. I. Bukhman

Endocrinology research center of RAMS


Russian Federation


T. L. Kurayeva

Endocrinology research center of RAMS


Russian Federation


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Review

For citations:


Remizov O.V., Bukhman A.I., Kurayeva T.L. Osseous changes in the foot of a diabetic child. Problems of Endocrinology. 1995;41(5):23-24. (In Russ.) https://doi.org/10.14341/probl11474

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)