Osseous changes in the foot of a diabetic child
https://doi.org/10.14341/probl11474
Abstract
Diabetic osteoarthropathy (DOAP) is a serious complication of diabetes mellitus (DM) and occurs, as a rule, in people over 30 years old. In most cases, DOAP is observed in women with insulin-dependent diabetes and with a disease duration of more than 10 years. The frequency of this complication ranges from 0.2 to 0.5%. DOAP is characterized by a unilateral lesion of the feet. Early clinical symptoms are thickening and erythema of the skin. As the disease progresses, deformations of bones and joints develop. Radiologically in these cases, osteolysis, osteoporosis, bone fragmentation, joint disintegration are determined. A histological examination, as a rule, reveals an increase in osteoclastic activity with bone resorption and proliferation of connective tissue, as well as aseptic vascular necrosis.
About the Authors
O. V RemizovEndocrinology research center of RAMS
Russian Federation
A. I. Bukhman
Endocrinology research center of RAMS
Russian Federation
T. L. Kurayeva
Endocrinology research center of RAMS
Russian Federation
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Review
For citations:
Remizov O.V., Bukhman A.I., Kurayeva T.L. Osseous changes in the foot of a diabetic child. Problems of Endocrinology. 1995;41(5):23-24. (In Russ.) https://doi.org/10.14341/probl11474

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