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Somatostatin analogues in the treatment of neuroendocrine system tumors

https://doi.org/10.14341/probl11628

Abstract

In recent years, significant progress has been made in understanding the biology and functional significance of somatostatin receptors (rCST) in various human tumors. The presence of functional rCST in tumors has clinical significance, which includes the ability, first, to control hormonal hypersecretion and the corresponding clinical symptoms through treatment with somatostatin analogues (SST); secondly, to conduct CCT scintigraphy, allowing in vivo to establish CCT-positive tumors and their metastases, and thirdly, to carry out pct-targeted radiotherapy using radiolabeled CST analogues.

About the Authors

I. I. Dedov

Endocrinological Research Center of RAMS


Russian Federation


V. V. Vaks

Endocrinological Research Center of RAMS


Russian Federation


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Review

For citations:


Dedov I.I., Vaks V.V. Somatostatin analogues in the treatment of neuroendocrine system tumors. Problems of Endocrinology. 2004;50(6):42-48. (In Russ.) https://doi.org/10.14341/probl11628

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