Serum leptin levels in obese children operated on for craniopharyngioma
https://doi.org/10.14341/probl11671
Abstract
The study was undertaken to investigate the concentrations of leptin after surgical treatment of craniopharyngioma. Patients with obesity were studied. There were the following 3 groups: 1) 8 boys and 2 girls aged 15.6+0.8 years after surgical treatment of craniopharyngioma; 2) 10 boys and 10 girls aged 8.48±0.45 years who had constitutional obesity and stage i puberty (after tanner);and3) loboysand logirlsaged 12.31+0.44years who had constitutional obesity and tanner stages ii-v puberty. There were no significant changes in the levels of leptin in prepubertal children. There was an age-related change in the concentration of leptin in girls, i.e. A significant increase in puberty. After surgical treatment of craniopharyngioma, the obese boys had lower levels of leptin than the comparison group boys with the same degree of sexual development and body weight values. There was a positive correlation of the levels of leptin and the body mass index in all age groups of patients with exogenous constitutional obesity.
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Review
For citations:
Solntseva A.V. Serum leptin levels in obese children operated on for craniopharyngioma. Problems of Endocrinology. 2003;49(4):16-18. (In Russ.) https://doi.org/10.14341/probl11671
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