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The use of the drug Wessel Duet F in the complex treatment of lesions of the lower extremities in patients with type II diabetes

https://doi.org/10.14341/probl11760

Abstract

A comprehensive approach to treatment of ischemic involvement of the lower limbs in patients with type 2 diabetes is proposed. Diabetics often develop obliterating atherosclerosis of the lower limb arteries; the risk of amputation of feet and shins, involving invalidism and death, is rather high. The authors assessed the effect of Vessel Due F (Alfa Wasserman, Italy) on lipid metabolism, blood rheology, and peripheral hemodynamics in 30 patients with type 2 diabetes complicated by the ischemic form of diabetic foot. The course of therapy lasted for 12 weeks. Lipid metabolism notably improved (total cholesterol level decreased), normocoagulation and normalization of peripheral arterial blood flow were attained in the majority of patients, as shown by dopplerography. Therefore, the drug is effective in the treatment of ischemic form of the lower limb involvement in patients with type 2 diabetes.

About the Authors

A. Yu. Tokmakova

Endocrinology Research Center RAMS


Russian Federation


T. M. Milenkaya

Endocrinology Research Center RAMS


Russian Federation


L. D. Chirkova

Endocrinology Research Center RAMS


Russian Federation


M. I. Arbuzova

Endocrinology Research Center RAMS


Russian Federation


M. B. Antsiferov

Endocrinology Research Center RAMS


Russian Federation


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Review

For citations:


Tokmakova A.Yu., Milenkaya T.M., Chirkova L.D., Arbuzova M.I., Antsiferov M.B. The use of the drug Wessel Duet F in the complex treatment of lesions of the lower extremities in patients with type II diabetes. Problems of Endocrinology. 1999;45(3):14-18. (In Russ.) https://doi.org/10.14341/probl11760

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)